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Abstract Microfluidic‐based wearable electrochemical sensors represent a transformative approach to non‐invasive, real‐time health monitoring through continuous biochemical analysis of body fluids such as sweat, saliva, and interstitial fluid. These systems offer significant potential for personalized healthcare and disease management by enabling real‐time detection of key biomarkers. However, challenges remain in optimizing microfluidic channel design, ensuring consistent biofluid collection, balancing high‐resolution fabrication with scalability, integrating flexible biocompatible materials, and establishing standardized validation protocols. This review explores advancements in microfluidic design, fabrication techniques, and integrated electrochemical sensors that have improved sensitivity, selectivity, and durability. Conventional photolithography, 3D printing, and laser‐based fabrication methods are compared, highlighting their mechanisms, advantages, and trade‐offs in microfluidic channel production. The application section summarizes strategies to overcome variability in biofluid composition, sensor drift, and user adaptability through innovative solutions such as hybrid material integration, self‐powered systems, and AI‐assisted data analysis. By analyzing recent breakthroughs, this paper outlines critical pathways for expanding wearable sensor technologies and achieving seamless operation in diverse real‐world settings, paving the way for a new era of digital health.more » « lessFree, publicly-accessible full text available March 18, 2026
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Abstract The development of wireless implantable sensors and integrated systems, enabled by advances in flexible and stretchable electronics technologies, is emerging to advance human health monitoring, diagnosis, and treatment. Progress in material and fabrication strategies allows for implantable electronics for unobtrusive monitoring via seamlessly interfacing with tissues and wirelessly communicating. Combining new nanomaterials and customizable printing processes offers unique possibilities for high‐performance implantable electronics. Here, this report summarizes the recent progress and advances in nanomaterials and printing technologies to develop wireless implantable sensors and electronics. Advances in materials and printing processes are reviewed with a focus on challenges in implantable applications. Demonstrations of wireless implantable electronics and advantages based on these technologies are discussed. Lastly, existing challenges and future directions of nanomaterials and printing are described.more » « less
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Abstract The advancement in virtual reality/augmented reality (VR/AR) has been achieved by breakthroughs in the realistic perception of virtual elements. Although VR/AR technology is advancing fast, enhanced sensor functions, long‐term wearability, and seamless integration with other electronic components are still required for more natural interactions with the virtual world. Here, this report reviews the recent advances in multifunctional wearable sensors and integrated functional devices for VR/AR applications. Specified device designs, packaging strategies, and interactive physiological sensors are summarized based on their methodological approaches for sensory inputs and virtual feedback. In addition, limitations of the existing systems, key challenges, and future directions are discussed. It is envisioned that this progress report's outcomes will expand the insights on wearable functional sensors and device interfaces toward next‐generation VR/AR technologies.more » « less
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